Importance of randomization in microarray experimental designs with Illumina platforms.

Nucleic Acids Res · 2009 · PMC2761262 · PMID 19617374

Europe PMC DOI

hedged sentence

0.0460

closest p · 0.9× alpha

0.0460

boldest claim

The sentences

a positive trendP -value = 0.046actually significant

a decreasing trendP -value = 0.09so close (0.05 < p ≤ 0.1)

In addition, we observed position effects: (i) in the Confounded experiment, a positive trend was observed in Chip 2 ( R 2 ∼ 0.25, P -value = 0.046); (ii) in the Randomized experiment, a decreasing trend across positions was observed in both chips ( R 2 ∼ 0.17, P -value = 0.09).

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