An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis.

All three models were highly significant, confirming the robustness of the classifier method ( P = 0.0001, P = 0.0002, and P = 0.0003, for 3-, 4- and 5- nearest neighbours models, respectively.

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No statistically significant variation was observed in the CD4+ lymphocyte compartment, although an increasing trend in CD4+CD25+ cell numbers could be observed in the non-responder group ( Figure 4 ).

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