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Targeted vs. systematic early antiviral treatment against A(H1N1)v influenza with neuraminidase inhibitors in patients with influenza-like symptoms: clinical and economic impact.

PLoS Curr · 2009 · PMC2768144 · PMID 20029659

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a decreasing trendno p-value reported
This study showed that the average time between onset of symptoms and antiviral treatment initiation in 1,810 patients was 2.2 days, with a decreasing trend from week 28 (4.0 days) to week 32 (2.0 days) of the analysis.

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