Barely Significant
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Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation.

BMC Endocr Disord · 2009 · PMC2768727 · PMID 19814797

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The final combined therapy reduced IGF-1 to lower levels than single therapy with either LASSA or PEG but the difference just failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.