Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways.

Bioinformatics · 2009 · PMC2773259 · PMID 19744994

Europe PMC DOI

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closest p · 0.0× alpha

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highly significantP = 1.7 × 10 −9actually significant

Extending our analysis to groups of functionally related proteins, we find statistically significant associations for gap junction proteins, connexins, which show a highly significant connection to hyperkeratosis ( Supplementary Table S5 , P = 1.7 × 10 −9 ).

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