Evolution of virulence in malaria.

J Biol · 2008 · PMC2776394 · PMID 18771591

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extremely significantno p-value reported

[ 2 ], the cytokines of the innate immune response play an extremely significant role in both the prevention and the exacerbation of severe disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.