Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a nonspatial decision-making maze task.

Subsequent analysis of simple main effects, exploring the significant group × block interaction, revealed a highly significant group difference on the first block of reversal 2 ( F 1,19 = 15.82, P < 0.005).

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Furthermore, although the deficit was statistically robust, the OFC-lesioned rats were only impaired during the initial day of reversal 2, and were indistinguishable from controls on reversals 1 and 3 (there was a nonsignificant trend towards impairment on reversal 4).

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