High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo.

BMC Cancer · 2009 · PMC2779818 · PMID 19912635

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

borderline significancep = 0.059so close (0.05 < p ≤ 0.1)

The correlation with cytoplasmic RelA/p65 expression showed borderline significance (p = 0.059, Table 1 ).

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borderline significantno p-value reported

Furthermore, nuclear RelA/p65 as well as cytoplasmic (borderline significant) RelA/p65 positivity was linked to increased HDAC expression when comparing the distributions of raw expression data, which suggests at least in part a transcriptional regulation and not only a post transcriptional modification of RelA/p65 activity by HDACs.

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