Barely Significant
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DNA asymmetric strand bias affects the amino acid composition of mitochondrial proteins.

DNA Res · 2007 · PMC2779903 · PMID 17974594

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The sentences

highly significantP < 0.0001actually significant
Despite the variations between species within both groups, there is a large average difference between them and this difference between the groups is statistically highly significant ( P < 0.0001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.