Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses.

Comparison of the 3 respective pre-test responses demonstrated an increase in the magnitude of the IL-10 response, particularly with regards to ST1 and ST2, but this trend was not quite significant ( Fig. 3 , p = 0.0562).

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