Barely Significant
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Assessment of breast cancer opportunistic screening by clinical-pathological indicators: a population-based study.

Br J Cancer · 2009 · PMC2788260 · PMID 19861962

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a decreasing trendno p-value reported
A decreasing trend of mean (APC:−1.3; 95% CI: −2.1; −0.5) and median (APC:−1.5; 95% CI: −2.5; −0.4) tumour size was detected from 1996 to 2007.

also in 47,180 other papers

an increasing trendno p-value reported
The incidence trend in pre-menopausal women was substantially stable (APC: −0.7; 95% CI: −4.7; 3.5), whereas at ages 50–69 and 70+ years, an increasing trend was observed, though the estimated APCs were not statistically significant.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.