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A quick guide for developing effective bioinformatics programming skills.

PLoS Comput Biol · 2009 · PMC2791169 · PMID 20041221

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an increasing trendno p-value reported
Additionally, we encourage proficiency in the use and maintenance of a Web server system, such as Apache [21] , as a survey of the bioinformatics literature clearly demonstrates an increasing trend towards the Web-based development, delivery, and utilization of bioinformatics tools and services.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.