Barely Significant
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The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells.

PLoS One · 2009 · PMC2793515 · PMID 20041182

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The sentences

highly significantno p-value reported
p<0.05 was considered significant (*), p<0.001 was considered very significant (**) and p<0.0001 was considered highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.