Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

Br J Cancer · 2009 · PMC2795432 · PMID 19920816

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marginally significantP =0.05actually significant

We observed a marginally significant association of the G allele in ERCC4 -rs744154 with breast cancer risk for both BRCA1 (HR: 0.78, 95% CI: 0.60–1.00, P =0.05) and BRCA2 (HR: 0.68, 95% CI: 0.45–1.02, P =0.06) mutation carriers.

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