Analysis of the frequencies of mRNAs having 20 nt long stretches with 70% U in the 3′ UTR ( Figure 2 D) revealed that 80% of the HuD targets have this characteristic, a value that was highly significant when compared to the genome, chip and forebrain datasets.
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Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.
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