Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila.

We next treated Aβ flies carrying a loss-of-function mutation of dFKBP59 , which showed a highly significant increase in lifespan, relative to non-BCS treated flies ( Fig. 4B ; P = 0.0001).

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