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A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer.

J Exp Clin Cancer Res · 2009 · PMC2803447 · PMID 20015348

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an increasing trendno p-value reported
There is an increasing trend towards multimodal treatments.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.