Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma.

BMC Cancer · 2009 · PMC2804715 · PMID 20028503

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

borderline significanceP = 0.065so close (0.05 < p ≤ 0.1)

The results showed that T status, CRT response and M-lym status were independent predictors of LPFS, while H3K27me3 expression only showed a borderline significance ( P = 0.065, Table 3 ).

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highly significantno p-value reported

Moreover, an imbalance of H3K27 methylation owing to overexpression of EZH2 has been implicated in metastatic prostate and aggressive breast cancers [ 8 , 9 ], in which a highly significant overlap between PRC2- and H3K27me3-occupied genes was observed [ 8 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.