Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice.

PLoS One · 2010 · PMC2809117 · PMID 20098623

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highly significantno p-value reported

Approaches aimed at obtaining protection from all potential modes of transmission are highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.