Lipopolysaccharide modifies amiloride-sensitive Na+ transport processes across human airway cells: role of mitogen-activated protein kinases ERK 1/2 and 5.

Phosphorylated ERK1/2 proteins were detected after 10 min, reached maximal levels at 60–120 min ( p < 0.05, n = 3), and although reduced, were still present after an overnight treatment with LPS although this did not quite reach significance ( p = 0.06, n = 3; Fig. 6a, b ).

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