Also, a highly significant correlation has been demonstrated between the percent decrease in the urinary NTX level at 3 or 6 months and the percent increase in the lumbar BMD after 2 years of alendronate treatment. 10 , 11 It has also been confirmed that a daily dose of 10 mg was more effective than one of 5 mg in suppressing bone resorption and increasing the lumbar BMD in patients with osteoporosis. 12 These results suggest that when bone resorption is more strongly suppressed, especially in the early period in osteoporosis treatment, there is a greater increase in BMD, which supports our results.
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Comparison of effect of treatment with etidronate and alendronate on lumbar bone mineral density in elderly women with osteoporosis.
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