Multimodal surface-based morphometry reveals diffuse cortical atrophy in traumatic brain injury.

The joint assessment of all four metrics using the Fisher combined probability test detected highly significant abnormalities in the frontal lobes bilaterally (p < 0.001) as well as the right occipital lobe (p < 0.01) on both imaging sessions (Table 2 , final two rows).

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Assessment of the cortical surface curvature similarity between the patient and controls revealed marginally significant differences in fine cortical structure in the left frontal, left parietal and bilateral temporal lobes on the first scanning session.

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