Effects of treatment for tobacco dependence on resting cerebral glucose metabolism.

To determine their relative contributions to the ‘active-treatments' analysis, we considered the bupropion HCl and PGC groups separately, and (compared with placebo-treated individuals) smokers treated with PGC had a greater reduction in glucose metabolism with treatment in the posterior cingulate gyrus, whereas those treated with bupropion HCl showed a trend towards significance in the same region.

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We found highly significant effects of treatment on CPD, exhaled CO, UTS, and FTND, but not on HAM-A or HAM-D ( Table 2 ).

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