There were no significant differences between the LPS and saline-treated animals for the pnd 7 + 9 or pnd 14 + 16 animals (P > 0.05), despite a slight trend towards a delay in the pnd 7 + 9 group ( Fig 1 ).
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Neonatal lipopolysaccharide exposure delays puberty and alters hypothalamic Kiss1 and Kiss1r mRNA expression in the female rat.
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