One trial administering perioperative teicoplanin prophylaxis showed a highly significant reduction (rate ratio 0.26, 0.15 to 0.45), 63 while all other trials, including those of the general setting, showed no significant differences, both individually and pooled.
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Prophylactic antibiotics for burns patients: systematic review and meta-analysis.
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The sentences
Perioperative systemic antibiotic prophylaxis had an advantage of borderline significance (0.72 (0.52 to 1.01), four trials), while general systemic and topical antibiotics had no effect.