Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions.

Mol Syst Biol · 2009 · PMC2824492 · PMID 20029368

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highly significantno p-value reported

We showed in two ways that the differential effects of ERK1 and ERK2 are highly significant: in a two-factorial analysis of variance with the null hypothesis ‘over-expression of ERK1 and ERK2 has the same effect on proliferation', the null hypothesis is dismissed with a P -value of 2.3 × 10 −9 .

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