High GC content: critical parameter for predicting stress regulated miRNAs in Arabidopsis thaliana.

Bioinformation · 2009 · PMC2825596 · PMID 20198191

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may be significantno p-value reported

The high GC content may be significant because of two reasons ‐ firstly the higher GC ratio gives a higher chance of complementarities with the coding regions also having a higher GC ratio, secondly since GC pair is bound by 3 hydrogen bonds, these bonds are more stable, so the miRNA binding and degradation of the target genes may be more probable.

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