Immune modulation by Schistosoma mansoni antigens in NOD mice: effects on both innate and adaptive immune systems.

J Biomed Biotechnol · 2010 · PMC2830582 · PMID 20204176

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Further analysis of the liver of SEA-treated NOD mice revealed a highly significant increase in Foxp3 + Tregs, which is consistent with the fact that Tregs are found in the egg-induced granulomas in the liver and regulate their formation ( Figure 6(b) ) [ 31 , 32 ].

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