Hypervariable intronic region in NCX1 is enriched in short insertion-deletion polymorphisms and showed association with cardiovascular traits.

Despite a three fold reduction in sample size compared to the full CADCZ patient group, the analysis of CAD patients with metabolic syndrome revealed highly significant association with increased effect size ( P = 0.0014, OR = 2.34; P = 0.0016, OR = 2.41; additive and dominant models, respectively).

also in 132,142 other papers

Association of the 14 bp indel with serum triglyceride levels reached marginal significance in the CADCZ sample ( P = 0.04, beta = 0.25; both models) and a non-significant trend for association in the joint meta-analysis with HYPEST data ( P = 0.08, beta = 0.18; P = 0.07, beta = 0.19; additive and dominant models, respectively).

also in 5,069 other papers