Barely Significant
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Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion.

J Exp Med · 2010 · PMC2839144 · PMID 20176801

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a decreasing trendno p-value reported
In the same experiment, CD8 + lymphocytes exhibited a decreasing trend in the ADV–Tim-3–treated group, but no statistically significant difference was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.