PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.

PLoS One · 2010 · PMC2841187 · PMID 20305782

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Since there may be significant potential in therapies targeting the novel pathological pathways, it is crucial to understand the molecular mechanisms involved in cardiac pathophysiology, especially ones specifically operated in the hearts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.