Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion.

The increased stability of the 1, N 2 -εdG lesion in the absence of the complementary dC correlates with the one-base deletion extension product observed during the bypass of the 1, N 2 -εdG lesion by the Dpo4 polymerase, suggesting that stabilization of this bulged intermediate may be significant with regard to the biological processing of the lesion.

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