Need-based up-regulation of protein levels in response to deletion of their duplicate genes.

PLoS Biol · 2010 · PMC2846854 · PMID 20361019

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marginally significantno p-value reported

We found that paralog responsiveness is strongly enriched in gene pairs with SSL interactions ( Figure 3 ; p = 0.004, Fisher exact test), and very rarely observed in genes with neutral genetic interactions ( Table S2 ; the only exceptions are VHS2 and CUE4 , which show marginally significant paralog responsiveness).

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