The highly significant constraints in non-synonymous substitution rates (Ka/Ks < 1.0) estimated in the overall evolution of the CCT8L family (Table 4 , foreground genes: "All CCT8L1/2") indicated that the CCT8L sequences are genes generally expressing functional proteins.
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Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes.
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