Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994.

The regression model for HDL (main effects only, Table 2 ) showed that 2,4-D was associated with a borderline significant 5% decrease of HDL when all available subjects were included (β-coefficient = -0.048, 95% CI [-0.101, 0.006], p-value = 0.08), and a significant 9% decrease for subjects in the lower 50% of T4 (β-coefficient = -0.09, 95% CI [-0.160, -0.016], p-value = 0.02).

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The two confidence intervals for the log(HDL) terms did not overlap, which was in line with the highly significant p-value of 0.006 for the log(HDL)*2,4-D interaction term.

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