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Design and optimization of diclofenac sodium controlled release solid dispersions by response surface methodology.

Indian J Pharm Sci · 2008 · PMC2852056 · PMID 20390076

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an increasing trendno p-value reported
The values of the Higuchi rate constant was found to vary between 17.38±0.52 to 25.22±0.72% h −1⁄2 showing an increasing trend with decrease in the polymer payloads and increase in Eudragit RL levels.

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