Barely Significant
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Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose.

PLoS One · 2010 · PMC2854692 · PMID 20418955

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highly significantno p-value reported
While further work will be required to elucidate the precise mechanism at play, the observed efficacy without increasing baseline blood glucose levels may be highly significant in enabling novel therapies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.