Comparing the tumors with no or positive hilar lymphnode metastases (pN0 and pN1) with those having already spread to mediastinal lymphnodes (pN2 and pN3) a statistical trend (percentage of positive cells) and a statistical significance (staining intensity) for an increase of LDH5 expression was found (table 2 ).
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Lactate-dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1.
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