A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses.

PLoS One · 2010 · PMC2862707 · PMID 20454659

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highly significantno p-value reported

GO analyses and GSEA revealed highly significant enriched functional gene categories for most of the clusters ( Tables S4 , S5 and S6 ). a) Non-transformed cells Genes whose response to 3D Matrigel culture (cluster 1+2; Figure 4a ; Table S4 ) was restricted to non-transformed cells were mainly related to ECM turnover, lipid and eicosanoid/prostaglandin metabolism, or cell differentiation.

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