A novel role for Wnt/Ca2+ signaling in actin cytoskeleton remodeling and cell motility in prostate cancer.

Integration of area under the curve revealed a 55%, 25% and 45% increase in the total area, average size and area fraction (total area /total pixels), representing the extent and intensity of staining, in malignant cores (n = 301) compared to benign cores (n = 299), respectively ( Fig 1E, F and G ) that were highly significant (p<0.0001, Student's t-test).

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