The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.

BMC Genomics · 2010 · PMC2865497 · PMID 20346131

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highly significantno p-value reported

Overall, the zinc finger array of each ortholog group showed strong purifying selection (ω = dN/dS around 0.1) with mostly highly significant p-values.

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