For widths 10, 12 and 14 bp, the distribution of Ontologizer P -values showed a sharp peak of highly significant P -values for the first 50 iterations, followed by a long flat tail of insignificant P -values punctuated by occasional marginally significant groups.
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Conserved elements associated with ribosomal genes and their trans-splice acceptor sites in Caenorhabditis elegans.
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The sentences
Large gene groups will be highly significant even when only a minority of the genes fall into the same category.