Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment.

Arthritis Res Ther · 2010 · PMC2875639 · PMID 20096109

Europe PMC DOI

hedged sentence

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

a trend toward significanceP = 0.064so close (0.05 < p ≤ 0.1)

This was confirmed in the validation group of 18 patients by using the mean expression levels of the three IFN response genes ( RSAD2 , IFI44L , and OAS1 ) measured by qPCR, although a trend toward significance was observed (Spearman R = -0.44, P = 0.064).

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