Barely Significant
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Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region.

J Hum Genet · 2010 · PMC2876206 · PMID 20300121

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highly significantno p-value reported
Nevertheless, a highly significant association of the non-synonymous SNP C80T and opioid dependence was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.