Growth parameters and calcium homeostasis in cystic fibrosis patients with CFTR I1234V mutation.

1 Pancreatic insufficiency (PI) can be a major factor, 2 but other factors including insulin resistance, bone disease, hepatobiliary dysfunction and vitamin D deficiency may be significant risk factors for defective bone growth. 3 The cystic fibrosis transmembrane conductance regulator (CFTR) I1234V mutation, with normal exocrine pancreatic function, is a common mutation among Arabs in the Arabian Gulf region. 4 Growth and nutritional parameters and FEV 1 were measured in 40 CF patients with CFTR I1234V mutation, (22 males and 18 females) from 22 families arising from a single large Arab kindred tribe attending the CF clinic at Hamad Medical Corporation, Qatar.

also in 13,097 other papers