Internal gallbladder drainage prevents development of acute cholecystitis in a pig model: a randomized study.

Using a histopathological scoring system based on the presence, extent and severity of hemorrhage, edema, formation of pregranulation tissue, lymphatic dilatation, and PMC infiltration in the gallbladder wall, we found a highly significant protective effect of internal drainage from the gallbladder to the duodenum in the development of acute cholecystitis.

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