A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease.

We used p-values defined by Lander and Kruglyak [ 17 ] to represent specific LOD score thresholds: (1) suggestive linkage with p value = 0.00074 and corresponding LOD = 2.2; (2) significant linkage with p-value = 0.00002 and corresponding LOD = 3.6; and (3) highly significant linkage with p- value = 0.0000003 and corresponding LOD = 5.4.

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