A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

PLoS One · 2010 · PMC2892470 · PMID 20593013

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0460

boldest claim

The sentences

highly significantp = 9.70×10 −10actually significant

When the Class II and Class III SNPs were included in the logistic regression model, the rs4959039 SNP retained a highly significant association with MS susceptibility ( p = 9.70×10 −10 , odds ratio = 1.52).

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borderline level of statistical significancep = .046actually significant

Despite the small size of this family based dataset, a borderline level of statistical significance was observed ( p = .046) supporting the validity of this SNP as an MS susceptibility locus using a family-based association test.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.