Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing.

PRRS is characterized with high mortality in piglets, reproductive failure (late-term abortions and stillbirths, premature farrowing, mummified pigs) in pregnant sows and respiratory disease (interstitial pneumonia, respiratory difficulties) in nursery and grower/finishing pigs, causing highly significant economic losses to the swine industry worldwide, resulting in >$ 560.32 million losses each year in the US alone [4] .

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