The miR-144/451 locus is required for erythroid homeostasis.

J Exp Med · 2010 · PMC2901075 · PMID 20513743

Europe PMC DOI

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closest p · 0.0× alpha

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The sentences

highly significantP < 8 × 10 −13actually significant

Sylamer analysis using all 7-nt motifs complementary to seed regions of mouse miRNAs revealed a highly significant (P < 8 × 10 −13 ; Bonferroni corrected < 7 × 10 −10 ) enrichment for the 7-nt seed match of miR-451 (AACGGTT) in the 3′ UTRs of genes in a cohort of 588 genes, most of which were up-regulated in miR144/451 −/− erythroid precursors ( Fig. 4 B ).

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